Journal article
Antidepressant medications and osteoporosis
Abstract
Use of antidepressant medications that act on the serotonin system has been linked to detrimental impacts on bone mineral density (BMD), and to osteoporosis. This article reviews current evidence for such effects, and identifies themes for future research. Serotonin receptors are found in all major types of bone cell (osteoblasts, osteocytes, and osteoclasts), indicating an important role of the neuroendocrine system in bone. Observational …
Authors
Rizzoli R; Cooper C; Reginster J-Y; Abrahamsen B; Adachi JD; Brandi ML; Bruyère O; Compston J; Ducy P; Ferrari S
Journal
Bone, Vol. 51, No. 3, pp. 606–613
Publisher
Elsevier
Publication Date
September 2012
DOI
10.1016/j.bone.2012.05.018
ISSN
8756-3282