Journal article
Dabigatran versus Warfarin in Patients with Mechanical Heart Valves
Abstract
BACKGROUND: Dabigatran is an oral direct thrombin inhibitor that has been shown to be an effective alternative to warfarin in patients with atrial fibrillation. We evaluated the use of dabigatran in patients with mechanical heart valves.
METHODS: In this phase 2 dose-validation study, we studied two populations of patients: those who had undergone aortic- or mitral-valve replacement within the past 7 days and those who had undergone such …
Authors
Eikelboom JW; Connolly SJ; Brueckmann M; Granger CB; Kappetein AP; Mack MJ; Blatchford J; Devenny K; Friedman J; Guiver K
Journal
New England Journal of Medicine, Vol. 369, No. 13, pp. 1206–1214
Publisher
Massachusetts Medical Society
Publication Date
September 26, 2013
DOI
10.1056/nejmoa1300615
ISSN
0028-4793