Behavioral effects of dopamine agonists across the estrous cycle in rats
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The effects of apomorphine upon stereotypy and bromocriptine upon wheel running and intracranial reward were examined across the estrous cycle of female rats. Apomorphine elicited sterotypy in a dose-related fashion, but sterotypy was not reliably or systematically altered by estrous conditions. On the other hand, wheel running was augmented by bromocriptine in an estrous-specific fashion. Self-stimulation was increased by bromocriptine but this was not related to estrous cyclicity. These findings provide evidence for possible behavioral and motivational specificity of dopamine (DA) receptor-related estrous changes.
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