Journal article
Antidepressant Effect of Ingested Nicotine in Female Rats of Flinders Resistant and Sensitive Lines
Abstract
Both major depression and depressive symptoms are associated with a high rate of nicotine dependence, and a history of major depression has an adverse impact on smoking cessation. The main objective of this study was to investigate whether continuous ingestion of nicotine affects indices of depressive behavior in the rat. We compared cholinergic- and serotonergic-hypersensitive Flinders Sensitive Line rats (FSL), a genetic animal model of …
Authors
Djurić VJ; Dunn E; Overstreet DH; Dragomir A; Steiner M
Journal
Physiology & Behavior, Vol. 67, No. 4, pp. 533–537
Publisher
Elsevier
Publication Date
October 1999
DOI
10.1016/s0031-9384(99)00091-8
ISSN
0031-9384