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A comparison of cholecystokinin-induced changes in...
Journal article

A comparison of cholecystokinin-induced changes in gastric emptying and feeding in rats

Abstract

We have compared the abilities of the cholecystokinin octapeptide (CCK-8) to delay gastric emptying and to influence feeding under similar experimental conditions in the rat. The effect of CCK-8 on gastric emptying was assessed in 6-h-deprived rats receiving 10-ml intragastric test loads of 0.15 M saline or 15% (wt/vol) sucrose. Analysis of half-emptying times indicated that intraperitoneal administration of CCK-8 in doses of 1.4-22.4 …

Authors

Conover KL; Collins SM; Weingarten HP

Journal

American Journal of Physiology, Vol. 255, No. 1, pp. r21–r26

Publisher

American Physiological Society

Publication Date

July 1, 1988

DOI

10.1152/ajpregu.1988.255.1.r21

ISSN

0002-9513