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Impaired sympathetic nerve function in the...
Journal article

Impaired sympathetic nerve function in the inflamed rat intestine

Abstract

The effect of intestinal inflammation on norepinephrine release from the myenteric plexus in the Trichinella spiralis-infected rat was assessed. Longitudinal muscle-myenteric plexus preparations were preincubated with [3H]norepinephrine and release was evoked by electrical field stimulation and KCl administration. Preincubation of preparations with desipramine or pretreatment of rats with 6-hydroxydopamine significantly suppressed the uptake …

Authors

Swain MG; Blennerhassett PA; Collins SM

Journal

Gastroenterology, Vol. 100, No. 3, pp. 675–682

Publisher

Elsevier

Publication Date

1991

DOI

10.1016/0016-5085(91)80011-w

ISSN

0016-5085