Journal article
The phenotypic manifestations of rare genic CNVs in autism spectrum disorder
Abstract
Significant evidence exists for the association between copy number variants (CNVs) and Autism Spectrum Disorder (ASD); however, most of this work has focused solely on the diagnosis of ASD. There is limited understanding of the impact of CNVs on the ‘sub-phenotypes’ of ASD. The objective of this paper is to evaluate associations between CNVs in differentially brain expressed (DBE) genes or genes previously implicated in ASD/intellectual …
Authors
Merikangas AK; Segurado R; Heron EA; Anney RJL; Paterson AD; Cook EH; Pinto D; Scherer SW; Szatmari P; Gill M
Journal
Molecular Psychiatry, Vol. 20, No. 11, pp. 1366–1372
Publisher
Springer Nature
Publication Date
November 2015
DOI
10.1038/mp.2014.150
ISSN
1359-4184