Journal article
Bidirectional communication between sleep and circadian rhythms and its implications for depression: Lessons from agomelatine
Abstract
Depression is a family of complex and multifactorial illnesses that are characterized by disruptions in the functioning of a number of physiological, neuroendocrine and behavioral processes. Of these, sleep disturbance and circadian rhythm abnormalities constitute the most prevalent signs of depressive illness. Difficulty in falling asleep, decreases in total sleep time and sleep efficiency, early morning awakenings, and rapid eye movement …
Authors
Pandi-Perumal SR; Moscovitch A; Srinivasan V; Spence DW; Cardinali DP; Brown GM
Journal
Progress in Neurobiology, Vol. 88, No. 4, pp. 264–271
Publisher
Elsevier
Publication Date
August 2009
DOI
10.1016/j.pneurobio.2009.04.007
ISSN
0301-0082