Journal article
Measurement of melatonin in body fluids: Standards, protocols and procedures
Abstract
Background and PurposeThe circadian rhythm of melatonin in saliva or plasma, or of the melatonin metabolite 6-sulfatoxymelatonin (a6MTs) in urine, is a defining feature of suprachiasmatic nucleus (SCN) function, the body’s endogenous oscillatory pacemaker. The primary objective of this review is to ascertain the clinical benefits and limitations of current methodologies employed for detection and quantification of melatonin in biological fluids …
Authors
de Almeida EA; Di Mascio P; Harumi T; Warren Spence D; Moscovitch A; Hardeland R; Cardinali DP; Brown GM; Pandi-Perumal SR
Journal
Child's Nervous System, Vol. 27, No. 6, pp. 879–891
Publisher
Springer Nature
Publication Date
June 2011
DOI
10.1007/s00381-010-1278-8
ISSN
0256-7040