Drug-Induced Stomatocytosis and Anemia During Consolidation Chemotherapy of Childhood Acute Leukemia

In a group of 23 children with acute leukemia, all but one of whom had entered complete remission, retrospective analysis of hematological profiles demonstrated that administration of consolidation chemotherapy, with a combination of cytosine arabinoside (Ara-C) and 6-thioguanine (TG), was associated with a fall in the erythrocyte concentration in peripheral blood, the rate of which was at least as fast as would have occurred with total marrow …