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Pulmonary Deposition of Salbutamol Aerosol...
Journal article

Pulmonary Deposition of Salbutamol Aerosol Delivered by Metered Dose Inhaler, Jet Nebulizer, and Ultrasonic Nebulizer in Mechanically Ventilated Rabbits

Abstract

The deposition efficiency of three methods of aerosol delivery of salbutamol into lungs of ventilated rabbits was compared: 1) metered dose inhaler (MDI) with holding chamber (HC), 2) jet nebulizer (JN), and 3) ultrasonic (US) nebulizer. The latter system was tested using two different sized medication reservoirs, a large (20 mL) cup (US20) and a small (10 mL) cup (US10). After delivery of technetium-99m-labeled sulbutamol aerosol, deposition …

Authors

Fok T-F; Al-Essa M; Monkman S; Dolovich M; Girard L; Coates G; Kirpalani H

Journal

Pediatric Research, Vol. 42, No. 5, pp. 721–727

Publisher

Springer Nature

Publication Date

November 1997

DOI

10.1203/00006450-199711000-00027

ISSN

0031-3998