Journal article
Effects of interleukin-6 and leukemia inhibitory factor on the acute phase response and DNA synthesis in cultured rat hepatocytes.
Abstract
Human recombinant interleukin-6 (IL-6) and human recombinant leukemia inhibitory factor (LIF) similarly stimulate synthesis of typical acute-phase proteins in the primary rat hepatocyte cultures. LIF is, however, less effective in increasing uptake of alpha-aminoisobutyric acid than IL-6. Antiserum to human IL-6 abolishes induced protein synthesis and amino acid uptake elicited by hrIL-6 but has no effect on the acute-phase response of rat …
Authors
Kordula T; Rokita H; Koj A; Fiers W; Gauldie J; Baumann H
Journal
Journal of Interferon & Cytokine Research, Vol. 10, No. 1-2, pp. 23–26
Publication Date
April 1991
ISSN
1079-9907