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Coordinate expression of group II phospholipase A2...
Journal article

Coordinate expression of group II phospholipase A2 and the acute-phase proteins haptoglobin (HP) and α1-anti-chymotrypsin (ACH) by HepG2 cells

Abstract

The early response to inflammation is characterized by the synthesis of a variety of proteins under cytokine and glucocorticoid control. During episodes of infection or inflammation, a secretory phospholipase A2 (sPLA2) appears in the circulation along with a variety of acute-phase proteins (APP), suggesting possible common regulatory elements amongst sPLA2 and APP. Using the human hepatoma line, HepG2, regulation of sPLA2 expression was …

Authors

VADAS P; GROUIX B; STEFANSKI E; WLOCH M; PRUZANSKI W; SCHROEDER J; GAULDIE J

Journal

Clinical & Experimental Immunology, Vol. 108, No. 1, pp. 175–180

Publisher

Oxford University Press (OUP)

Publication Date

October 29, 2003

DOI

10.1046/j.1365-2249.1997.d01-990.x

ISSN

0009-9104