Journal article
Crosslinking of collagen with dendrimers
Abstract
Polypropyleneimine octaamine dendrimers were studied as an alternative means of generating highly crosslinked collagen. Crosslinking was effected by using the water-soluble carbodiimide 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide hydrochloride (EDC). The multifunctional dendrimers were introduced as novel crosslinkers after the activation of the carboxylic acid groups of glutamic and aspartic acid residues in collagen. The conventional …
Authors
Duan X; Sheardown H
Journal
Journal of Biomedical Materials Research Part A, Vol. 75A, No. 3, pp. 510–518
Publisher
Wiley
Publication Date
12 2005
DOI
10.1002/jbm.a.30475
ISSN
1549-3296