Solid-phase analytical derivatization: enhancement of sensitivity and selectivity of analysis

Analytical derivatizations enhance the sensitivity and selectivity of determinations for organic compounds. Classical techniques are often based on solution chemistry. Most modern sample preparation techniques, however, are based on solid-phase extractions. Solid-phase analytical derivatization bridges this gap and facilitates sample preparation by combining the isolation step with the derivatization. The solid-phase retains both reagents and …