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Relationship between Tissue Sensitization and IgE...
Journal article

Relationship between Tissue Sensitization and IgE Antibody Production in Rats Infected with the Nematode, Nippostrongylus brasiliensis

Abstract

In Nippostrongylus brasiliensis rats, tracheal sensitivity to worm allergens developed prior to intestinal sensitivity and correlated with the early local synthesis of reaginic antibody in the mediastinal (bronchial) lymph nodes. Skin and intestinal sensitivity to worm allergens more nearly correlated with serum reaginic antibody and its synthesis by mesenteric lymph nodes and other tissues. Prostaglandins appeared to modulate intestinal …

Authors

Befus AD; Johnston N; Berman L; Bienenstock J

Journal

International Archives of Allergy and Applied Immunology, Vol. 67, No. 3, pp. 213–218

Publisher

Karger Publishers

Publication Date

1982

DOI

10.1159/000233021

ISSN

0020-5915