Journal article
Partial Separation and Functional Characterization of Guinea Pig Basophil-Stimulating Factor
Abstract
We have previously described T lymphocyte dependent guinea pig basophil growth from bone marrow precursors in vitro. In the current studies, basophil-stimulating factor (BSF) present in mitogen-stimulated splenic conditioned medium (CM) has been functionally characterized, utilizing an assay for BSF on nonadherent bone marrow target cells. BSF was found to be heat stable, nondialyzable, and inactivated by proteases. Monosaccharides known to …
Authors
Denburg JA; Davison M; Bienenstock J
Journal
International Archives of Allergy and Applied Immunology, Vol. 79, No. 3, pp. 312–319
Publisher
Karger Publishers
Publication Date
1986
DOI
10.1159/000233993
ISSN
0020-5915