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Glial cells express multiple ATP binding cassette...
Journal article

Glial cells express multiple ATP binding cassette proteins which are involved in ATP release

Abstract

Rat brain astrocyte and microglia cultures express different members of ATP-binding-cassette (ABC) proteins. RT-PCR analysis showed that astrocytes are equipped with P-glycoprotein (mdr1a, mdr1b), multidrug resistance-associated-protein (mrp1, mrp4, mrp5) and cystic fibrosis transmembrane conductance regulator (CFTR). No transcripts for mrp5 and CFTR were detected in microglia. The ABC protein functional activities are shown by the following …

Authors

Ballerini P; Di Iorio P; Ciccarelli R; Nargi E; D'Alimonte I; Traversa U; Rathbone MP; Caciagli F

Journal

Neuroreport, Vol. 13, No. 14, pp. 1789–1792

Publisher

Wolters Kluwer

Publication Date

October 2002

DOI

10.1097/00001756-200210070-00019

ISSN

0959-4965