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Delayed, ferrous iron-dependent peroxidation of...
Journal article

Delayed, ferrous iron-dependent peroxidation of rat liver microsomes

Abstract

Measurement of both chemiluminescence (CL) and the formation of 2-thiobarbituric acid-reacting substances (TBAR) has been used to study the delayed, nonenzymatic lipid peroxidation (LP) initiated in rat liver microsomes by ferrous chloride. Following Fe2+ addition, the CL technique revealed a burst of light emission (peak, Phase II) which was preceded by a period of little or no detectable photon production (delay, Phase I) and succeeded by an …

Authors

Goddard JG; Sweeney GD

Journal

Archives of Biochemistry and Biophysics, Vol. 259, No. 2, pp. 372–381

Publisher

Elsevier

Publication Date

December 1987

DOI

10.1016/0003-9861(87)90503-0

ISSN

0003-9861