Journal article
Comparison of the in vivo hemorrhagic and antithrombotic effects of a low antithrombin-iii affinity heparin fraction
Abstract
Antithrombin III (ATIII) affinity chromatography of commercial grade heparin yields fractions of high and low affinity for ATIII. In vitro, the high affinity fraction accounts for most of the anticoagulant effect while there is evidence that the low affinity material interferes with platelet function. We have studied the relative antithrombotic and hemorrhagic effects of low affinity heparin. The low affinity heparin fraction, specific activity …
Authors
Ockelford PA; Carter CJ; Cerskus A; Smith CA; Hirsh J
Journal
Thrombosis Research, Vol. 27, No. 6, pp. 679–690
Publisher
Elsevier
Publication Date
9 1982
DOI
10.1016/0049-3848(82)90006-8
ISSN
0049-3848