The Anatomical and Pathological Characteristics of Irradiated Prostate Cancers May Influence the Oncological Efficacy of Salvage Ablative Therapies

PURPOSE: Recurrent or radioresistant prostate cancer occurs in approximately 30% of men receiving primary radiotherapy. For men who are candidates for local salvage therapy, the oncological efficacy of ablative therapies may be affected by the anatomical and pathological features of cancers within irradiated prostate glands. We characterized and mapped the prostate cancers in our series of whole mount salvage radical prostatectomy specimens.