Catalytic promiscuity of glycopeptide N-methyltransferases enables bio-orthogonal labelling of biosynthetic intermediates Academic Article uri icon

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abstract

  • Remarkable promiscuity of N-methyltransferases enables modulation of biological activity as well as bio-orthogonal labelling of glycopeptide antibiotics and biosynthetic intermediates.

authors

  • Brieke, Clara
  • Yim, Grace
  • Peschke, Madeleine
  • Wright, Gerard
  • Cryle, Max J

publication date

  • November 17, 2016