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Probiotic Bifidobacterium longum NCC3001 Reduces...
Journal article

Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome

Abstract

BACKGROUND & AIMS: Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but little is known about their effects on psychiatric comorbidities. We performed a prospective study to evaluate the effects of Bifidobacterium longum NCC3001 (BL) on anxiety and depression in patients with IBS. METHODS: We performed a randomized, double-blind, placebo-controlled study of 44 adults with IBS and diarrhea or a mixed-stool pattern (based on Rome …

Authors

Pinto-Sanchez MI; Hall GB; Ghajar K; Nardelli A; Bolino C; Lau JT; Martin F-P; Cominetti O; Welsh C; Rieder A

Journal

Gastroenterology, Vol. 153, No. 2, pp. 448–459.e8

Publisher

Elsevier

Publication Date

August 2017

DOI

10.1053/j.gastro.2017.05.003

ISSN

0016-5085