Journal article
Dose-related effects of propericiazine in rats
Abstract
We evaluated the effects of the neuroleptic agent propericiazine on animal models of anxiety and memory. Adult male Wistar rats (250 to 350 g) received intraperitoneal injections of propericiazine (0.05, 0.075 and 0.1 mg/kg), diazepam (1 mg/kg), saline, or diazepam vehicle (20% propylene glycol and 80% saline) 30 min prior to the experimental procedure. Animals (10-15 for each task) were tested for step-down inhibitory avoidance (0.3-mA …
Authors
Cechin EM; Quevedo J; Barichello T; Machado-Vieira R; Gentil V; Kapczinski F
Journal
Brazilian Journal of Medical and Biological Research, Vol. 36, No. 2, pp. 227–231
Publisher
FapUNIFESP (SciELO)
Publication Date
February 2003
DOI
10.1590/s0100-879x2003000200010
ISSN
0100-879X