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Maintenance N-acetyl cysteine treatment for...
Journal article

Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial

Abstract

BackgroundN-acetyl cysteine (NAC) is a glutathione precursor that has been shown to have antidepressant efficacy in a placebo-controlled trial. The current study aimed to investigate the maintenance effects of NAC following eight weeks of open-label treatment for bipolar disorder.MethodThe efficacy of a double blind randomized placebo controlled trial of 2 g/day NAC as adjunct maintenance treatment for bipolar disorder was examined. …

Authors

Berk M; Dean OM; Cotton SM; Gama CS; Kapczinski F; Fernandes B; Kohlmann K; Jeavons S; Hewitt K; Moss K

Journal

BMC Medicine, Vol. 10, No. 1,

Publisher

Springer Nature

Publication Date

12 2012

DOI

10.1186/1741-7015-10-91

ISSN

1741-7015