Journal article
Tianeptine exerts neuroprotective effects in the brain tissue of rats exposed to the chronic stress model
Abstract
Animal models of chronic stress represent valuable tools by which to investigate the behavioral, endocrine and neurobiological changes underlying stress-related psychopathologies, such as major depression, and the efficacy of antidepressant therapies. The present study was aimed at investigating the neurochemical effects of the antidepressant tianeptine in rats exposed to the chronic stress model. To this aim, rats were subjected to 40days of …
Authors
Della FP; Abelaira HM; Réus GZ; Antunes AR; dos Santos MAB; Zappelinni G; Steckert AV; Vuolo F; Galant LS; Dal-Pizzol F
Journal
Pharmacology Biochemistry and Behavior, Vol. 103, No. 2, pp. 395–402
Publisher
Elsevier
Publication Date
December 2012
DOI
10.1016/j.pbb.2012.09.018
ISSN
0091-3057