Is bipolar disorder associated with accelerating aging? A meta-analysis of telomere length studies Academic Article uri icon

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  • BACKGROUND: Bipolar disorder (BD) is associated with a reduced life expectancy compared to the general population mainly due to a high prevalence of comorbid somatic illnesses. A model of accelerated aging has been proposed as a potential explanation to these epidemiological findings. Nevertheless, studies measuring telomere length (TL) in patients with BD compared to healthy controls have provided mixed results. OBJECTIVE: To compare TL between BD patients and healthy controls, and to search for potential modeP


  • Colpo, Gabriela D
  • Leffa, Daniella D
  • Köhler, Cristiano A
  • Kapczinski, Flavio
  • Quevedo, João
  • Carvalho, André F

publication date

  • November 2015