Journal article
The role of macrophage polarization on bipolar disorder: Identifying new therapeutic targets
Abstract
OBJECTIVE: Bipolar disorder is a chronic, severe and disabling disease; however, its pathophysiology remains poorly understood. Recent evidence has suggested that inflammation and immune dysregulation play a significant role in the pathophysiology of bipolar disorder. This review is aimed to highlight the importance of systemic inflammation in modulating the inflammatory response of microglia and hence its potential involvement with bipolar …
Authors
Ascoli BM; Géa LP; Colombo R; Barbé-Tuana FM; Kapczinski F; Rosa AR
Journal
Australian & New Zealand Journal of Psychiatry, Vol. 50, No. 7, pp. 618–630
Publisher
SAGE Publications
Publication Date
July 2016
DOI
10.1177/0004867416642846
ISSN
0004-8674