Tutorial review. Future prospects for the analysis of complex biological systems using micro-column liquid chromatography–electrospray tandem mass spectrometry Journal Articles uri icon

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  • An overview is provided of methods for the study of complex biological processes by using micro-column liquid chromatography-electrospray ionization tandem mass spectrometry. Procedures discussed include electrospray ionization, micro-column liquid chromatography, tandem mass spectrometry, tandem mass spectra data interpretation for peptides, and database searching with mass spectral data. Several problems in immunology are discussed to illustrate this approach.


  • Koutny, Maciej
  • Yates, John R
  • McCormack, Ashley L
  • Link, Andrew J
  • Schieltz, David
  • Eng, Jimmy
  • Hays, Lara

publication date

  • July 1996