Journal article
Cardiovascular responses to intrathecal administration of strychnine in the rat
Abstract
Experiments were done to determine the influence of spinal glycinergic mechanisms in regulating sympathetic output to the heart and vessels in the anaesthetized male Sprague-Dawley rat. Intrathecal administration of 65 (n = 6) and 130 (n = 8) nmol of strychnine, but not of a lower dose (32.5 nmol, n = 8), to the second thoracic segment increased heart rate within one minute (P less than 0.01). Similar administration of artificial cerebrospinal …
Authors
Hong Y; Yashpal K; Henry JL
Journal
Brain Research, Vol. 499, No. 1, pp. 169–173
Publisher
Elsevier
Publication Date
October 1989
DOI
10.1016/0006-8993(89)91148-7
ISSN
0006-8993