Journal article
Mast cell ionic channels: significance for stimulussecretion coupling
Abstract
The activation of mast cells (MC) due to immunological stimulation causes an immediate and dramatic inflammatory response. We review current evidence indicating that the membrane permeabilities for calcium, chloride, sodium, and potassium have a significant role in the activation of these cells, and in some cases, specific ionic channels have been identified. Moreover, a number of intracellular mechanisms controlling these channels are pointed …
Authors
Janiszewski J; Huizinga JD; Blennerhassett MG
Journal
Canadian Journal of Physiology and Pharmacology, Vol. 70, No. 1, pp. 1–7
Publisher
Canadian Science Publishing
Publication Date
January 1, 1992
DOI
10.1139/y92-001
ISSN
0008-4212