Journal article
Inwardly rectifying chloride channel activity in intestinal pacemaker cells
Abstract
Cl(-) channels are proposed to play a role in gut pacemaker activity, but little is known about the characteristics of Cl(-) channels in interstitial cells of Cajal (ICC), the intestinal pacemaker cells. The objective of the present study was to identify whole cell Cl(-) currents in ICC associated with previously observed single-channel activity and to characterize its inward rectification. Whole cell patch-clamp studies showed that ICC express …
Authors
Zhu Y; Mucci A; Huizinga JD
Journal
AJP Gastrointestinal and Liver Physiology, Vol. 288, No. 4, pp. g809–g821
Publisher
American Physiological Society
Publication Date
April 2005
DOI
10.1152/ajpgi.00301.2004
ISSN
0193-1857