Journal article
Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized
Abstract
The frequency of joint bleeds and orthopaedic joint scores were evaluated in 121 patients with severe haemophilia who had started prophylactic treatment with clotting factor concentrates at least once weekly before the age of 10. 75 of the patients started before the age of 3, 31 at the age of 3-5 and 15 at the age of 6-9. Each subgroup was evaluated separately. In addition, a regimen of one infusion weekly was compared with that of two …
Authors
Astermark J; Petrini P; Tengborn L; Schulman S; Ljung R; Berntorp E
Journal
British Journal of Haematology, Vol. 105, No. 4, pp. 1109–1113
Publisher
Wiley
Publication Date
June 1999
DOI
10.1046/j.1365-2141.1999.01463.x
ISSN
0007-1048