Journal article
Clinical significance of markedly elevated serum creatine kinase levels in patients with acne on isotretinoin.
Abstract
Muscle-related complaints and high creatine kinase (CK) blood levels have been reported in 16-51% of patients with acne treated with isotretinoin. It has been suggested that this retinoid and exercise have a synergistic effect on muscle. The presence of marked hyperCKemia during the treatment raises concern about rhabdomyolysis. The objective of this report was to evaluate the incidence, course and clinical significance of severe hyperCKemia in …
Authors
Landau M; Mesterman R; Ophir J; Mevorah B; Alcalay J; Harel A; Nevo Y
Journal
Acta Dermato Venereologica, Vol. 81, No. 5, pp. 350–352
Publisher
MJS Publishing, Medical Journals Sweden AB
Publication Date
November 1, 2001
DOI
10.1080/000155501317140070
ISSN
0001-5555