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Stroke in the TOTAL trial: a randomized trial of...
Journal article

Stroke in the TOTAL trial: a randomized trial of routine thrombectomy vs. percutaneous coronary intervention alone in ST elevation myocardial infarction

Abstract

AIMS: TOTAL (N = 10 732), a randomized trial of routine manual thrombectomy vs. percutaneous coronary intervention alone in ST elevation myocardial infarction, showed no difference in the primary efficacy outcome but a significant increase in stroke. We sought to understand these findings. METHODS AND RESULTS: A detailed analysis of stroke timing, stroke severity, and stroke subtype was performed. Strokes were adjudicated by neurologists …

Authors

Jolly SS; Cairns JA; Yusuf S; Meeks B; Gao P; Hart RG; Kedev S; Stankovic G; Moreno R; Horak D

Journal

European Heart Journal, Vol. 36, No. 35, pp. 2364–2372

Publisher

Oxford University Press (OUP)

Publication Date

September 14, 2015

DOI

10.1093/eurheartj/ehv296

ISSN

0195-668X