Journal article
Pacemaker or Defibrillator Surgery without Interruption of Anticoagulation
Abstract
BACKGROUND: Many patients requiring pacemaker or implantable cardioverter-defibrillator (ICD) surgery are taking warfarin. For patients at high risk for thromboembolic events, guidelines recommend bridging therapy with heparin; however, case series suggest that it may be safe to perform surgery without interrupting warfarin treatment. There have been few results from clinical trials to support the safety and efficacy of this approach.
METHODS: …
Authors
Birnie DH; Healey JS; Wells GA; Verma A; Tang AS; Krahn AD; Simpson CS; Ayala-Paredes F; Coutu B; Leiria TLL
Journal
New England Journal of Medicine, Vol. 368, No. 22, pp. 2084–2093
Publisher
Massachusetts Medical Society
Publication Date
May 30, 2013
DOI
10.1056/nejmoa1302946
ISSN
0028-4793