Journal article
IgA antibodies to myeloperoxidase in patients with eosinophilic granulomatosis with polyangiitis (Churg-Strauss).
Abstract
OBJECTIVES: To determine the prevalence of anti-myeloperoxidase (MPO) antibodies of IgA (IgA anti-MPO) isotype in patients with eosinophilic granulomatosis with polyangiitis (EGPA), and the association of the IgA antibodies with IgG anti-MPO and with disease activity.
METHODS: Serum samples from patients with EGPA followed in a multicenter longitudinal cohort were tested by ELISA for the presence of IgA anti-MPO and IgG anti-MPO antibodies. …
Authors
Oommen E; Hummel A; Allmannsberger L; Cuthbertson D; Carette S; Pagnoux C; Hoffman GS; Jenne DE; Khalidi NA; Koening CL
Journal
Clinical and Experimental Rheumatology, Vol. 35 Suppl 103, No. 1, pp. 98–101
Publication Date
2017
ISSN
0392-856X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdultAgedAged, 80 and overAntibodies, Antineutrophil CytoplasmicBiomarkersCanadaCase-Control StudiesChurg-Strauss SyndromeEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin AImmunoglobulin GImmunosuppressive AgentsMaleMiddle AgedPeroxidasePredictive Value of TestsRemission InductionTreatment OutcomeUnited StatesYoung Adult