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Developmental changes in the adhesive disk during...
Journal article

Developmental changes in the adhesive disk during Giardia differentiation

Abstract

Giardia lamblia is a protozoan parasite infecting the upper mammalian small intestine. Infection relies upon the ability of the parasite to attach to the intestine via a unique cytoskeletal organelle, the ventral disk. We determined the composition and structure of the disk throughout the life cycle of the parasite and identified a new disk protein, SALP-1. SALP-1 is an immunodominant protein related to striated fiber-assemblin (SFA). The disk …

Authors

Palm D; Weiland M; McArthur AG; Winiecka-Krusnell J; Cipriano MJ; Birkeland SR; Pacocha SE; Davids B; Gillin F; Linder E

Journal

Molecular and Biochemical Parasitology, Vol. 141, No. 2, pp. 199–207

Publisher

Elsevier

Publication Date

June 2005

DOI

10.1016/j.molbiopara.2005.03.005

ISSN

0166-6851