Journal article
Trophic effects of purines in neurons and glial cells
Abstract
In addition to their well known roles within cells, purine nucleotides such as adenosine 5' triphosphate (ATP) and guanosine 5' triphosphate (GTP), nucleosides such as adenosine and guanosine and bases, such as adenine and guanine and their metabolic products xanthine and hypoxanthine are released into the extracellular space where they act as intercellular signaling molecules. In the nervous system they mediate both immediate effects, such as …
Authors
Rathbone MP; Middlemiss PJ; Gysbers JW; Andrew C; Herman MAR; Reed JK; Ciccarelli R; Di Iorio P; Caciagli F
Journal
Progress in Neurobiology, Vol. 59, No. 6, pp. 663–690
Publisher
Elsevier
Publication Date
12 1999
DOI
10.1016/s0301-0082(99)00017-9
ISSN
0301-0082