Journal article
Interleukin-6 and interleukin-10 as acute kidney injury biomarkers in pediatric cardiac surgery
Abstract
BackgroundChildren undergoing cardiac surgery may exhibit a pronounced inflammatory response to cardiopulmonary bypass (CPB). Inflammation is recognized as an important pathophysiologic process leading to acute kidney injury (AKI). The aim of this study was to evaluate the association of the inflammatory cytokines interleukin (IL)-6 and IL-10 with AKI and other adverse outcomes in children after CPB surgery.MethodsThis is a sub-study of the …
Authors
Greenberg JH; Whitlock R; Zhang WR; Thiessen-Philbrook HR; Zappitelli M; Devarajan P; Eikelboom J; Kavsak PA; Devereaux PJ; Shortt C
Journal
Pediatric Nephrology, Vol. 30, No. 9, pp. 1519–1527
Publisher
Springer Nature
Publication Date
September 2015
DOI
10.1007/s00467-015-3088-4
ISSN
0931-041X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Acute Kidney InjuryAdolescentBiomarkersCanadaCardiac Surgical ProceduresCardiopulmonary BypassChildChild, PreschoolCohort StudiesCreatinineFemaleHumansInfantInterleukin-10Interleukin-6Kidney Function TestsMalePostoperative ComplicationsPredictive Value of TestsPreoperative CarePrognosisRenal DialysisUnited States