Journal article
Cognitive Function in Patients With Colorectal Cancer Who Do and Do Not Receive Chemotherapy: A Prospective, Longitudinal, Controlled Study
Abstract
PURPOSE: Cognitive dysfunction is reported in people with cancer. Therefore, we evaluated longitudinal changes in cognitive function and underlying mechanisms in people with colorectal cancer (CRC) and healthy controls (HCs).
PATIENTS AND METHODS: Participants completed cognitive assessments and questionnaires reporting cognitive symptoms, fatigue, quality of life, and anxiety/depression at baseline (before chemotherapy, if given) and 6, 12, …
Authors
Vardy JL; Dhillon HM; Pond GR; Rourke SB; Bekele T; Renton C; Dodd A; Zhang H; Beale P; Clarke S
Journal
Journal of Clinical Oncology, Vol. 33, No. 34, pp. 4085–4092
Publisher
American Society of Clinical Oncology (ASCO)
Publication Date
December 1, 2015
DOI
10.1200/jco.2015.63.0905
ISSN
0732-183X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedAntineoplastic Combined Chemotherapy ProtocolsCase-Control StudiesCognitionCognition DisordersColorectal NeoplasmsFatigueFemaleFollow-Up StudiesHumansLongitudinal StudiesLymphatic MetastasisMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingNeuropsychological TestsPrognosisProspective StudiesQuality of LifeSurveys and QuestionnairesYoung Adult