Mode of long-term antifertility effect of intrauterine neem treatment (IUNT)

The mode of antifertility action of intrauterine neem treatment (IUNT) was studied. The effect of IUNT on ovarian functions and uterine responsiveness to ovarian hormones was examined in adult Wistar rats. The treated animals had normal reproductive cycles as indicated by the vaginal smears; serum progesterone levels were also in the normal range. Effect of exogenous estradiol following IUNT in ovariectomized rats showed comparable uterine …