Journal article
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis
Abstract
Frank Costantini and colleagues report the identification of the ETS transcription factors, Etv4 and Etv5, as key targets of Ret signaling during kidney branching morphogenesis. Loss of Etv4 and Etv5 function in mice leads to complete failure of kidney development.
Authors
Lu BC; Cebrian C; Chi X; Kuure S; Kuo R; Bates CM; Arber S; Hassell J; MacNeil L; Hoshi M
Journal
Nature Genetics, Vol. 41, No. 12, pp. 1295–1302
Publisher
Springer Nature
Publication Date
December 2009
DOI
10.1038/ng.476
ISSN
1061-4036