Pseudofacilitation: A misleading term Journal Articles

abstract

• AbstractThe possible causes of the transient enlargement of muscle compound action potentials during repetitive stimulation (“pseudofacilitation”) are considered. The phenomenon cannot be due to mechanical artefact, while hypersynchronization of the muscle fiber action potentials, the usual explanation, can only make a minor contribution. A more convincing explanation, for which there is now experimental evidence, is that the muscle fibers undergo hyperpolarization, due to the intramuscular release of norepinephrine and consequent stimulation of the electrogenic Na+, K+‐pump. Defective phosphorylation of the Na+, K+‐pump is a possible cause of the transient weakness and myotonia in myotonic dystrophy. © 1994 John Wiley & Sons, Inc.

authors

• McComas, Alan John
• Galea, Vicki
• Einhorn, Roman W

status

• published 

publication date

• June 1994

has subject area

• 11 Medical and Health Sciences (FoR)
• Action Potentials (MeSH)
• Animals (MeSH)
• Electric Stimulation (MeSH)
• Electromyography (MeSH)
• Humans (MeSH)
• Muscle Contraction (MeSH)
• Muscles (MeSH)
• Neurology & Neurosurgery (Science Metrix)
• Reaction Time (MeSH)
• Sodium-Potassium-Exchanging ATPase (MeSH)

published in

• Muscle and Nerve  Journal

keywords

• Action Potentials
• Animals
• Electric Stimulation
• Electromyography
• Humans
• Muscle Contraction
• Muscles
• Reaction Time
• Sodium-Potassium-Exchanging ATPase

Digital Object Identifier (DOI)

• 10.1002/mus.880170606

PubMed ID

• 8196702

start page

• 599

end page

• 607

volume

• 17

issue

• 6