Journal article
Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice
Abstract
BACKGROUND AND AIMS: Abdominal pain and discomfort are common symptoms in functional disorders and are attributed to visceral hypersensitivity. These symptoms fluctuate over time but the basis for this is unknown. Here we examine the impact of changes in gut flora and gut inflammatory cell activity on visceral sensitivity.
METHODS: Visceral sensitivity to colorectal distension (CRD) was assessed at intervals in healthy mice for up to 12 weeks, …
Authors
Verdú EF; Bercik P; Verma-Gandhu M; Huang X-X; Blennerhassett P; Jackson W; Mao Y; Wang L; Rochat F; Collins SM
Journal
Gut, Vol. 55, No. 2,
Publisher
BMJ
Publication Date
February 2006
DOI
10.1136/gut.2005.066100
ISSN
0017-5749