Are brand‐name and generic warfarin interchangeable?

Although Health Canada approved generic warfarins in Year 2000, there is still controversy over the interchangeability of these products with brand‐name Coumadin. Since a large population of patients require warfarin and it has a narrow margin of efficacy and safety, it is vital to ensure that generic brands can be safely interchanged with Coumadin. Multiple N‐of‐1 randomized double blind crossover trials switched outpatients between generic …