An assessment of global health status in survivors of acute lymphoblastic leukemia in childhood.

PURPOSE: Progressive improvement in survival rates of children with cancer demands an appraisal of the "cost of cure." Much information is available on the frequency and severity of individual late effects in long-term survivors, but there are few data on multiple sequelae in individual patients or on global morbidity burdens. PATIENTS AND METHODS: To address this issue, we developed a multiattribute health status classification system. This …