Journal article
Heterogeneity in design and analysis of ICU delirium randomized trials: a systematic review
Abstract
BackgroundThere is a growing number of randomized controlled trials (RCTs) evaluating interventions to prevent or treat delirium in the intensive care unit (ICU). Efforts to improve the conduct of delirium RCTs are underway, but none address issues related to statistical analysis. The purpose of this review is to evaluate heterogeneity in the design and analysis of delirium outcomes and advance methodological recommendations for delirium RCTs …
Authors
Colantuoni E; Koneru M; Akhlaghi N; Li X; Hashem MD; Dinglas VD; Neufeld KJ; Harhay MO; Needham DM
Journal
Trials, Vol. 22, No. 1,
Publisher
Springer Nature
Publication Date
12 2021
DOI
10.1186/s13063-021-05299-1
ISSN
1468-6708