Journal article
Global Impact of Fixed-Dose Combination Therapies on Cardiovascular Mortality and Events, 2023-2050 A Modeling Study
Abstract
BACKGROUND: Uptake of drugs for primary and secondary prevention of cardiovascular disease is low in many countries. Single-pill combination (SPC) therapies consisting of a statin and 1 or more antihypertensive drugs, with or without aspirin, can reduce rates of fatal and nonfatal cardiovascular disease, but their use is currently limited.
OBJECTIVES: The authors modeled the potential impact of widespread adoption of SPC therapies over 2023 to …
Authors
Watkins DA; Pickersgill SJ; Flood D; Gaziano TA; Huffman MD; Islam S; Joseph P; Malekzadeh R; Perel P; Piñeiro DJ
Journal
Journal of the American College of Cardiology, Vol. 86, No. 3, pp. 149–161
Publisher
Elsevier
Publication Date
7 2025
DOI
10.1016/j.jacc.2025.04.043
ISSN
0735-1097