Host-like conditions validate nutrient transport as an antimalarial drug target. Journal Articles uri icon

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abstract

  • Antimalarial drug discovery largely relies on nutrient-rich media that may obscure physiologically relevant targets. In this issue of Cell Chemical Biology, Molina et al.1 validate the plasmodial surface anion channel as essential for Plasmodium falciparum survival under nutrient-restricted conditions, demonstrating how physiological media can expose druggable biology overlooked by standard screening approaches.

publication date

  • June 19, 2025